02 / Before any decision
Screening must account for the whole picture.
Ibogaine has been associated with potentially serious cardiac effects, and a proposed setting should not treat a questionnaire as a substitute for meaningful assessment.
A / CARDIAC
Heart risk requires particular care.
Cardiac history, fainting, palpitations, electrolyte concerns, and other risk factors may matter. An ECG and relevant laboratory work are commonly discussed as part of pre-treatment assessment. The U.S. FDA’s information on QT prolongation describes why changes in cardiac electrical timing can be clinically significant.
B / PSYCHIATRIC
Psychiatric history is part of safety review.
A careful evaluation should consider mood, psychosis, suicidality, trauma, sleep, support, and current stability. Altered-state experiences can be intense and unpredictable. The clinical framing of psychosis underscores why past or present symptoms deserve qualified attention rather than casual screening.
C / CONTEXT
The setting changes the risk.
Medical oversight, accurate disclosure, emergency equipment, transfer arrangements, and post-treatment follow-up can affect what happens when concerns arise. No setting can make an uncertain intervention risk-free, but absent planning is itself a meaningful warning sign.